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Article

Decreased Methylation Level of H3K27me3 Increases Seizure Susceptibility.

Molecular neurobiology - 1 Nov 2017

Wang Zhongcheng, Zhang Yusong, Fang Jian, Yu Fang, Heng Duanhe, Fan Yuanteng, Xu Jian, Peng Biwen, Liu Wanhong, Han Song, He Xiaohua

Abstract excerpt

Epigenetic modifications including histone modifications are associated with seizure development and epileptogenesis; however, its underlying mechanism remains to be elucidated. Dipeptidyl peptidase 4 (DPP4) and IL6 are identified as febrile seizure (FS)-related genes using gene microarray analysis in hyperthermia prone (HP) rats. This purpose of the study focused on exploring whether epigenetic modifications...

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Source

Identifiers

PMID: 27815838
DOI: 10.1007/s12035-016-0197-4

Genes

DPP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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