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Article

Role of Histone Deacetylases (HDACs) in Epilepsy and Epileptogenesis

9 Feb 2018

Abstract excerpt

BACKGROUND: Emerging evidence suggests that epigenetic mechanisms are involved in different brain functions such as the development of the nervous system and normal neuronal function. At the same time, it has been proposed that several neurological diseases are in part, caused by aberrant epigenetic modifications. Nevertheless, the mechanisms underlying pathological alterations in the brain genome are not...

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PMID: 29076408
DOI: 10.2174/1381612823666171024130001

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