Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphoma

4 Nov 2016

Abstract excerpt

The BCL6 (B-Cell Lymphoma 6) gene is a proto-oncogene that is often expressed in diffuse large B-cell lymphomas (DLBCLs). BCL6 loss of function can kill DLBCL cells, demonstrating that BCL6 is necessary for the survival of DLBCL cells and could be a therapeutic target. In this study, we found that BCL6 protein levels were consistently upregulated in DLBCL tissues, whereas its mRNA levels varied randomly in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circular RNAs in diseases
Share to Lymphoma Diagnosis and Treatment
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27815824
DOI: 10.1007/s13238-016-0316-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphomaPMID 27815824Read ↗

BCL6 represses NFκB activity in diffuse large B‐cell lymphomasSemantic proximity Read ↗

A Critical Role of miR-144 in Diffuse Large B-cell Lymphoma Proliferation and InvasionSemantic proximity Read ↗

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphomaSemantic proximity Read ↗

B Cell Lymphoma 6 (BCL6): A Conserved Regulator of Immunity and BeyondSemantic proximity Read ↗

BCL6 as a therapeutic target for lymphoma.Semantic proximity Read ↗

Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomasSemantic proximity Read ↗

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.Semantic proximity Read ↗

Molecular Pathogenesis of Non-Hodgkin's Lymphoma: the Role of Bcl-6Semantic proximity Read ↗

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomasSemantic proximity Read ↗

Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma.Semantic proximity Read ↗

Identification BCL6 and miR-30 family associating with Ibrutinib resistance in activated B-cell-like diffuse large B-cell lymphoma.Semantic proximity Read ↗

FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.