Article
Identification BCL6 and miR-30 family associating with Ibrutinib resistance in activated B-cell-like diffuse large B-cell lymphoma.
Medical oncology (Northwood, London, England) - 25 Feb 2021
Li Jiazheng, Huang Yan, Zhang Yun, Wen Jingjing, Chen Yanxin, Wang Lingyan, Jiang Peifang, Hu Jianda
Abstract excerpt
Ibrutinib has clear efficacy for activated B-cell-like diffuse large B cell lymphoma (ABC-DLBCL) in previous clinical researches. However, the resistance of Ibrutinib has limited its therapeutic benefit and the potential mechanism remains unclear. This study was aimed to identify potential candidate genes and miRNA targets to overcome Ibrutinib resistance in ABC-DLBCL. First, two expression profiles were...
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