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Article

Distinctive expression pattern of OCT4 variants in different types of breast cancer

1 Nov 2016

Abstract excerpt

BACKGROUND: OCT4 is a key regulator of self-renewal and pluripotency in embryonic stem cells which can potentially encode three spliced variants designated OCT4A, OCT4B and OCT4B1. Based on cancer stem cell concept, it is suggested that the stemness factors misexpressed in cancer cells and potentially is involved in tumorigenesis. OBJECTIVE: Accordingly, in this study, we investigated the potential expression of...

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Identifiers

PMID: 27814277
DOI: 10.3233/cbm-160675

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