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Article

Differential expression of Oct3/4 in human breast cancer and normal tissues

29 Mar 2018

Abstract excerpt

Oct3/4, a transcription factor specifically expressed in mammalian totipotent embryonic stem and germ cells, has a critical role in the regulation and maintenance of pluripotency and self-renewal. However, reactivation of Oct3/4 expression is observed in several human breast cancer cell lines, but not in non‑malignant cells. To examine Oct3/4 expression in human primary breast carcinomas and normal breast...

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Identifiers

PMID: 29620155
DOI: 10.3892/ijo.2018.4341

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