Article
Expression of the pluripotency markers Oct3/4, Nanog and Sox2 in human breast cancer cell lines
1 Jan 2012
Abstract excerpt
Previous studies have demonstrated that pluripotency-associated transcription factors, such as Oct3/4, Nanog and Sox2, play a crucial role in the development and malignant progression of various types of tumors. Breast cancer is the most frequent cancer among females, being a heterogeneous disease, with distinct morphologies, metastatic behavior and therapeutic responses. The expression of Oct3/4, Nanog and Sox2...
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