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Attributes of Oct4 in stem cell biology: perspectives on cancer stem cells of the ovary

21 Nov 2012

Abstract excerpt

Epithelial ovarian cancer (EOC) remains the most lethal of all the gynaecological malignancies with drug resistance and recurrence remaining the major therapeutic barrier in the management of the disease. Although several studies have been undertaken to understand the mechanisms responsible for chemoresistance and subsequent recurrence in EOC, the exact mechanisms associated with chemoresistance/recurrence...

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PMID: 23171809
DOI: 10.1186/1757-2215-5-37

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