Article
A 90-Day Feeding Study in Rats to Assess the Safety of Genetically Engineered Pork.
PloS one - 1 Jan 2016
Xiao Gao-Jun, Jiang Sheng-Wang, Qian Li-Li, Cai Chun-Bo, Wang Qing-Qing, Ma De-Zun, Li Biao, Xie Shan-Shan, Cui Wen-Tao, Li Kui
Abstract excerpt
Our laboratory recently produced genetically engineered (GE) Meishan pigs containing a ZFN-edited myostatin loss-of-function mutant. These GE pigs develop and grow as normal as wild type pigs but produce pork with greater lean yield and lower fat mass. To assess any potential subchronic toxicity risks of this GE pork, a 90-day feeding study was conducted in Sprague-Dawley rats. Rats were randomly divided into...
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