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Article

A Mutational Hotspot and Strong Selection Contribute to the Order of Mutations Selected for during Escherichia coli Adaptation to the Gut.

PLoS genetics - 1 Nov 2016

Lourenço Marta, Ramiro Ricardo S, Güleresi Daniela, Barroso-Batista João, Xavier Karina B, Gordo Isabel, Sousa Ana

Abstract excerpt

The relative role of drift versus selection underlying the evolution of bacterial species within the gut microbiota remains poorly understood. The large sizes of bacterial populations in this environment suggest that even adaptive mutations with weak effects, thought to be the most frequently occurring, could substantially contribute to a rapid pace of evolutionary change in the gut. We followed the emergence of...

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Identifiers

PMID: 27812114
DOI: 10.1371/journal.pgen.1006420
PMCID: PMC5094792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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