Association between polymorphisms in the promoter region of pri-miR-34b/c and risk of hepatocellular carcinoma.

doi:10.4238/gmr.15048723

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Article

Association between polymorphisms in the promoter region of pri-miR-34b/c and risk of hepatocellular carcinoma.

Genetics and molecular research : GMR - 5 Oct 2016

Chen L L, Shen Y, Zhang J B, Wang S, Jiang T, Zheng M Q, Zheng Z J, Chen C X

Abstract excerpt

Hepatocellular carcinoma (HCC) is a major cause of cancer-related deaths worldwide. MicroRNA-34 (miR-34) gene plays a key role in altering the apoptotic cycle and pathways of downstream cells, and therefore influences carcinogenesis. In this case-control study, we assessed the role of the pri-miR-34b/c rs4938723 polymorphism in HCC risk. The pri-miR-34b/c polymorphic genotype was determined in 286 patients with...

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PMID: 27808368
DOI: 10.4238/gmr.15048723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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