Article
Interaction of the Complexin Accessory Helix with Synaptobrevin Regulates Spontaneous Fusion.
Biophysical journal - 1 Nov 2016
Vasin Alexander, Volfson Dina, Littleton J Troy, Bykhovskaia Maria
Abstract excerpt
Neuronal transmitters are released from nerve terminals via the fusion of synaptic vesicles with the plasma membrane. Vesicles attach to membranes via a specialized protein machinery composed of membrane-attached (t-SNARE) and vesicle-attached (v-SNARE) proteins that zipper together to form a coiled-coil SNARE bundle that brings the two fusing membranes into close proximity. Neurotransmitter release may occur...
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