Article
Complexin has opposite effects on two modes of synaptic vesicle fusion.
Current biology : CB - 25 Jan 2011
Martin Jesse A, Hu Zhitao, Fenz Katherine M, Fernandez Joel, Dittman Jeremy S
Abstract excerpt
BACKGROUND: Synaptic transmission can occur in a binary or graded fashion, depending on whether transmitter release is triggered by action potentials or by gradual changes in membrane potential. Molecular differences of these two types of fusion events and their differential regulation in a physiological context have yet to be addressed. Complexin is a conserved SNARE-binding protein that has been proposed to...
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