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Article

[[Research Progress in Escape Mutations of the Human Immunodeficiency Virus under Pressure of HLA-Restricted Cytotoxic T Lymphocytes].

Bing du xue bao = Chinese journal of virology - 1 May 2015

Shi Yin, Wan Yanmin, Xu Jianqing

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes (CTLs) play a critical role in the control of HIV-1 infection and replication. HIV-1 evades CTL mediated pressure through viral escape mutations within targeted CTLs epitopes or flanking regions, but this process is usually associated with a viral fitness cost. The mutated epitopes may weaken the level of the original CTL responses,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26470538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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