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Article

Different in vivo effects of HIV-1 immunodominant epitope-specific cytotoxic T lymphocytes on selection of escape mutant viruses.

Journal of virology - 1 Jun 2010

Koizumi Hirokazu, Hashimoto Masao, Fujiwara Mamoru, Murakoshi Hayato, Chikata Takayuki, Borghan Mohamed Ali, Hachiya Atsuko, Kawashima Yuka, Takata Hiroshi, Ueno Takamasa, Oka Shinichi, Takiguchi Masafumi

Abstract excerpt

HIV-1 escape mutants are well known to be selected by immune pressure via HIV-1-specific cytotoxic T lymphocytes (CTLs) and neutralizing antibodies. The ability of the CTLs to suppress HIV-1 replication is assumed to be associated with the selection of escape mutants from the CTLs. Therefore, we first investigated the correlation between the ability of HLA-A*1101-restricted CTLs recognizing immunodominant...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20335254
DOI: 10.1128/JVI.02483-09
PMCID: PMC2876605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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