Article
Mechanisms of HIV-1 escape from immune responses and antiretroviral drugs.
Current opinion in immunology - 1 Aug 2004
Bailey Justin, Blankson Joel N, Wind-Rotolo Megan, Siliciano Robert F
Abstract excerpt
Despite the fact that HIV-1 induces vigorous antiviral immune responses, viral replication is never completely controlled in infected individuals. Recent studies have provided insight into the mechanisms by which focused immune pressure directed at particular B or T cell epitopes leads to the rapid appearance of escape mutations. Even if anti-HIV-1 immune responses could be enhanced to the point where they...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
