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Article

Determination of natural moisturizing factors in the skin: Raman microspectroscopy versus HPLC.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Sept 2017

Koppes S A, Kemperman P, Van Tilburg I, Calkoen-Kwa F, Engebretsen K A, Puppels G J, Caspers P J, Kezic S

Abstract excerpt

BACKGROUND: Natural moisturizing factor (NMF) is used as genotypic and phenotypic biomarker in diagnostics. This study is a side-to-side comparison of two different methods to determine NMF in atopic dermatitis patients: Raman microspectroscopy and stratum corneum tape stripping followed by HPLC. RESULTS: Measured NMF values were significantly correlated (R2 = .61; p < .0001), both methods demonstrated a...

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Source

Identifiers

PMID: 27805415
DOI: 10.1080/1354750X.2016.1256428

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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