Article
New Therapeutic Approaches for Fibrosing Skin Diseases: An Ecofriendly UVA-1 Permissive Sunscreen Formulation Which Displays Activity at the Aryl Hydrocarbon Receptor. A Potential Cost Effective and Convenient Therapeutic Approach to Fibrosing Skin Di
2024-09-03
Abstract excerpt
UVA1 phototherapy has been reported to mediate some of its effects via FICZ/AHR/MAPK signaling. A proof-of-concept study was performed to assess whether a topical solution of L tryptophan formulated to favor the generation 6-formylindolo[3,2-b] carbazole (FICZ) demonstrated activity at the aryl hydrocarbon receptor (AHR) as assessed by the intensity of cytochrome P450 1A2 staining. Ten participants applied a trial...
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Identifiers and source
- Literature Corpus work
- c4dfc9ef-7ced-5583-8a75-42554d68b567
- DOI
- 10.20944/preprints202408.2232.v1
