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Article

Impact of filaggrin mutations on Raman spectra and biophysical properties of the stratum corneum in mild to moderate atopic dermatitis.

Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Aug 2012

Mlitz V, Latreille J, Gardinier S, Jdid R, Drouault Y, Hufnagl P, Eckhart L, Guinot C, Tschachler E

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) is associated with null mutations in the filaggrin (FLG) gene. OBJECTIVE: To assess the impact of FLG null mutations on biophysical properties and the molecular composition of the stratum corneum (SC) in healthy individuals and AD patients. METHODS: A total of 196 French adults, including 97 with a history of mild to moderate AD, were genotyped for the three major European FLG...

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Source

Identifiers

PMID: 21812836
DOI: 10.1111/j.1468-3083.2011.04198.x

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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