Article
Extension of Health Span and Life Span in Drosophila by S107 Requires the calstabin Homologue FK506-BP2.
The Journal of biological chemistry - 9 Dec 2016
Kreko-Pierce Tabita, Azpurua Jorge, Mahoney Rebekah E, Eaton Benjamin A
Abstract excerpt
The accumulation of oxidative damage is strongly linked to age-dependent declines in cell function, but the contribution of oxidative damage to morbidity is still debated. Many organisms seem to tolerate oxidative damage, and the extension of health span and life span by augmenting antioxidant activity has been inconsistent. Here we use the Drosophila model system to investigate the relationship among oxidative...
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