Article

A familial natural short sleep mutation promotes healthy aging and extends lifespan in <i>Drosophila</i>

2023-04-26

Abstract excerpt

<h4>Summary</h4> Sleep loss typically imposes negative effects on animal health. However, humans with a rare genetic mutation in the dec2 gene ( dec2 P384R ) present an exception; these individuals sleep less without the usual effects associated with sleep deprivation. Thus, it has been suggested that the dec2 P384R mutation activates compensatory mechanisms that allows these individuals to thrive with less...

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Literature Corpus work: 9b0a6caa-f2c8-5237-af3f-ddcb5b03ef04
DOI: 10.1101/2023.04.25.538137

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