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Article

Drosophila p38 MAPK interacts with BAG-3/starvin to regulate age-dependent protein homeostasis.

Aging cell - 1 Nov 2021

Ryan Sarah M, Almassey Michael, Burch Amelia M, Ngo Gia, Martin Julia M, Myers David, Compton Devin, Archie Shira, Cross Megan, Naeger Lauren, Salzman Ashley, Virola-Iarussi Alyssa, Barbee Scott A, Mortimer Nathan T, Sanyal Subhabrata, Vrailas-Mortimer Alysia D

Abstract excerpt

As organisms age, they often accumulate protein aggregates that are thought to be toxic, potentially leading to age-related diseases. This accumulation of protein aggregates is partially attributed to a failure to maintain protein homeostasis. A variety of genetic factors have been linked to longevity, but how these factors also contribute to protein homeostasis is not completely understood. In order to...

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Identifiers

PMID: 34674371
DOI: 10.1111/acel.13481
PMCID: PMC8590102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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