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Article

Evidence for mitochondrial genetic control of autosomal gene expression.

Human molecular genetics - 15 Dec 2016

Kassam Irfahan, Qi Tuan, Lloyd-Jones Luke, Holloway Alexander, Jan Bonder Marc, Henders Anjali K, Martin Nicholas G, Powell Joseph E, Franke Lude, Montgomery Grant W, Visscher Peter M, McRae Allan F

Abstract excerpt

The mitochondrial and nuclear genomes coordinate and co-evolve in eukaryotes in order to adapt to environmental changes. Variation in the mitochondrial genome is capable of affecting expression of genes on the nuclear genome. Sex-specific mitochondrial genetic control of gene expression has been demonstrated in Drosophila melanogaster, where males were found to drive most of the total variation in gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27798101
DOI: 10.1093/hmg/ddw347
PMCID: PMC6078603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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