Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitonuclear Interactions Mediate Transcriptional Responses to Hypoxia in Drosophila.

Molecular biology and evolution - 1 Feb 2017

Mossman Jim A, Tross Jennifer G, Jourjine Nick A, Li Nan, Wu Zhijin, Rand David M

Abstract excerpt

Among the major challenges in quantitative genetics and personalized medicine is to understand how gene × gene interactions (G × G: epistasis) and gene × environment interactions (G × E) underlie phenotypic variation. Here, we use the intimate relationship between mitochondria and oxygen availability to dissect the roles of nuclear DNA (nDNA) variation, mitochondrial DNA (mtDNA) variation, hypoxia, and their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Cell Nucleus
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Hypoxia

Share to Mitochondria

Share to Transcriptional Activation

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 28110272
DOI: 10.1093/molbev/msw246
PMCID: PMC6095086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitonuclear Interactions Mediate Transcriptional Responses to Hypoxia in Drosophila.PMID 28110272Read ↗

Mitonuclear conflict and cooperation govern the integration of genotypes, phenotypes and environments.Semantic proximity Read ↗

Mitochondrial-Nuclear Interactions Mediate Sex-Specific Transcriptional Profiles in Drosophila.Semantic proximity Read ↗

Mito-nuclear interactions as drivers of gene movement on and off the X-chromosomeSemantic proximity Read ↗

Mitonuclear interactions: evolutionary consequences over multiple biological scales.Semantic proximity Read ↗

Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster.Semantic proximity Read ↗

Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel.Semantic proximity Read ↗

Experimental evidence supports a sex-specific selective sieve in mitochondrial genome evolution.Semantic proximity Read ↗

Mitochondrial genotype alters the impact of rapamycin on the transcriptional response to nutrients in Drosophila.Semantic proximity Read ↗

Evidence for mitochondrial genetic control of autosomal gene expression.Semantic proximity Read ↗

Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster.Semantic proximity Read ↗

Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations.Semantic proximity Read ↗

Quantitative evaluation of the mitochondrial proteomes of Drosophila melanogaster adapted to extreme oxygen conditions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.