Article
MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2016
Chen Jian, Zhu Rong-Fang, Li Fang-Fang, Liang Yu-Lai, Wang Chen, Qin Yong-Wen, Huang Shuang, Zhao Xian-Xian, Jing Qing
Abstract excerpt
OBJECTIVE: MicroRNA-126 (miR-126) is an endothelium-enriched miRNA and functions in vascular integrity and angiogenesis. The application of miRNA as potential biomarker and therapy target has been widely investigated in various pathological processes. However, its role in lymphatic diseases had not been widely explored. We aimed to reveal the role of miR-126 in lymphangiogenesis and the regulatory signaling...
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