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Article

mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish.

Genes & development - 1 Aug 2015

Koltowska Katarzyna, Paterson Scott, Bower Neil I, Baillie Gregory J, Lagendijk Anne K, Astin Jonathan W, Chen Huijun, Francois Mathias, Crosier Philip S, Taft Ryan J, Simons Cas, Smith Kelly A, Hogan Benjamin M

Abstract excerpt

The lymphatic vasculature plays roles in tissue fluid balance, immune cell trafficking, fatty acid absorption, cancer metastasis, and cardiovascular disease. Lymphatic vessels form by lymphangiogenesis, the sprouting of new lymphatics from pre-existing vessels, in both development and disease contexts. The apical signaling pathway in lymphangiogenesis is the VEGFC/VEGFR3 pathway, yet how signaling controls...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Vascular Endothelial Growth Factor C

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Source

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Identifiers

PMID: 26253536
DOI: 10.1101/gad.263210.115
PMCID: PMC4536310

Genes

VEGFC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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