Article
miR-126 regulates angiogenic signaling and vascular integrity.
Developmental cell - 1 Aug 2008
Fish Jason E, Santoro Massimo M, Morton Sarah U, Yu Sangho, Yeh Ru-Fang, Wythe Joshua D, Ivey Kathryn N, Bruneau Benoit G, Stainier Didier Y R, Srivastava Deepak
Abstract excerpt
Precise regulation of the formation, maintenance, and remodeling of the vasculature is required for normal development, tissue response to injury, and tumor progression. How specific microRNAs intersect with and modulate angiogenic signaling cascades is unknown. Here, we identified microRNAs that were enriched in endothelial cells derived from mouse embryonic stem (ES) cells and in developing mouse embryos. We...
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