Article
The genetic architecture of inflammatory bowel disease: past, present and future.
Current opinion in gastroenterology - 1 Nov 2015
Cleynen Isabelle, Vermeire Séverine
Abstract excerpt
PURPOSE OF REVIEW: Genome-wide association studies (GWAS) have helped to understand the genetic basis and pathogenesis of inflammatory bowel disease (IBD). However, understanding the functional and clinical consequences of the associated alleles has not followed the same pace. In this review, we discuss how studying the genetic predisposition to IBD has increased our understanding about IBD pathogenesis and how...
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