Article
Controlling the Rate of GWAS False Discoveries.
Genetics - 1 Jan 2017
Brzyski Damian, Peterson Christine B, Sobczyk Piotr, Candès Emmanuel J, Bogdan Malgorzata, Sabatti Chiara
Abstract excerpt
With the rise of both the number and the complexity of traits of interest, control of the false discovery rate (FDR) in genetic association studies has become an increasingly appealing and accepted target for multiple comparison adjustment. While a number of robust FDR-controlling strategies exist, the nature of this error rate is intimately tied to the precise way in which discoveries are counted, and the...
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