Correction for multiple testing in a gene region.

Abstract excerpt

Several methods to correct for multiple testing within a gene region have been proposed. These methods are useful for candidate gene studies, and to fine map gene-regions from GWAs. The Bonferroni correction and permutation are common adjustments, but are overly conservative and computationally intensive, respectively. Other options include calculating the effective number of independent single-nucleotide...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Data Interpretation, Statistical
• Share to Genetic Testing
• Share to Genome-Wide Association Study