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Article

Association of single nucleotide polymorphisms in the 5' upstream region of the C4BPA gene with essential hypertension in a northeastern Han Chinese population.

Molecular medicine reports - 1 Aug 2017

Liu Xueyan, Jiang Chao, Yang Ping

Abstract excerpt

A previous study of the authors using microarray analysis indicated that the expression of complement component 4 binding protein (C4BP)A is upregulated in essential hypertension (EH) patients, but the association between C4BPA variations and EH has not yet been clearly demonstrated. Since the 5' upstream region is known to serve important roles in the gene expression regulation, the present study aimed to...

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PMID: 28627632
DOI: 10.3892/mmr.2017.6736
PMCID: PMC5561803

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