Article
The common single-nucleotide polymorphism rs2681472 is associated with early-onset preeclampsia in Northern Han Chinese women.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Nov 2014
Wan Ji-Peng, Wang Hong, Li Chang-Zhong, Zhao Han, You Li, Shi Dong-Hong, Sun Xiu-Hua, Lv Hong, Wang Fei, Wen Ze-Qing, Wang Xie-Tong, Chen Zi-Jiang
Abstract excerpt
Preeclampsia, characterized by hypertension and proteinuria, remains a leading cause of maternal morbidity and mortality. Recently, a genome-wide association study (GWAS) identified the single-nucleotide polymorphism, rs2681472, as a new hypertension susceptibility genetic variant. The purpose of this study was to evaluate the association between preeclampsia and rs268172 in a Northern Han Chinese population. We...
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