Article
Immunoregulatory effects of 4-(4-chlorophenyl)-1-(5-amino-3-methylisoxazole-4-carbonyl)-thiosemicarbazide (06K) in non-immunized and SRBC-immunized mice.
The Journal of pharmacy and pharmacology - 1 Dec 2016
Drynda Angelika, Obmińska-Mrukowicz Bożena, Zaczyńska Ewa, Zimecki Michał, Ryng Stanisław, Mączyński Marcin
Abstract excerpt
OBJECTIVES: Immunoregulatory properties of 06K derivative (4-(4-chlorophenyl)-1-(5-amino-3-methylisoxazole-4-carbonyl)-thiosemicarbazide) in mouse in vivo models were investigated. METHODS: Several in vivo models were used: humoral and cellular immune response, carrageenan inflammatory reaction and determination of lymphocyte subsets in non-immunized mice. KEY FINDINGS: The compound administered before or after...
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