Article
A Role for Regulatory T Cells in a Murine Model of Epicutaneous Toluene Diisocyanate Sensitization.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Jul 2016
Long Carrie Mae, Marshall Nikki B, Lukomska Ewa, Kashon Michael L, Meade B Jean, Shane Hillary, Anderson Stacey E
Abstract excerpt
Toluene diisocyanate (TDI) is a leading cause of chemical-induced occupational asthma which impacts workers in a variety of industries worldwide. Recently, the robust regulatory potential of regulatory T cells (Tregs) has become apparent, including their functional role in the regulation of allergic disease; however, their function in TDI-induced sensitization has not been explored. To elucidate the kinetics,...
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