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Article

Touch imprint cytology with massively parallel sequencing (TIC-seq): a simple and rapid method to snapshot genetic alterations in tumors.

Cancer medicine - 1 Dec 2016

Amemiya Kenji, Hirotsu Yosuke, Goto Taichiro, Nakagomi Hiroshi, Mochizuki Hitoshi, Oyama Toshio, Omata Masao

Abstract excerpt

Identifying genetic alterations in tumors is critical for molecular targeting of therapy. In the clinical setting, formalin-fixed paraffin-embedded (FFPE) tissue is usually employed for genetic analysis. However, DNA extracted from FFPE tissue is often not suitable for analysis because of its low levels and poor quality. Additionally, FFPE sample preparation is time-consuming. To provide early treatment for...

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Identifiers

PMID: 27774772
DOI: 10.1002/cam4.950
PMCID: PMC5224853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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