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Article

Genetic profiling of thymic carcinoma using targeted next-generation sequencing.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2014

Shitara Masayuki, Okuda Katsuhiro, Suzuki Ayumi, Tatematsu Tsutomu, Hikosaka Yu, Moriyama Satoru, Sasaki Hidefumi, Fujii Yoshitaka, Yano Motoki

Abstract excerpt

OBJECTIVES: Thymic carcinoma is a rare mediastinal neoplasm and little is known about its tumorigenesis. There is no effective treatment except for complete resection, and the prognosis of advanced cases is poor. To identify the mutations associated with tumorigenesis, we analyzed genetic profile of thymic carcinoma using targeted next-generation sequencing. MATERIALS AND METHODS: We sequenced about 409...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25249426
DOI: 10.1016/j.lungcan.2014.08.020

Genes

KIT
DDR2
PDGFRA
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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