Article
Use of touch imprint cytology as a simple method to enrich tumor cells for molecular analysis.
Cancer cytopathology - 1 Jul 2013
Dogan Snjezana, Becker Jillian C, Rekhtman Natasha, Tang Laura H, Nafa Khedoudja, Ladanyi Marc, Klimstra David S
Abstract excerpt
BACKGROUND: A relative excess of nonneoplastic cells in frozen carcinoma samples is often a cause of false-negative results in molecular assays. Given the greater cohesiveness of epithelial tumor cells compared with nonneoplastic epithelium and mesenchymal stroma, the authors hypothesized that tumor procurement by touch imprinting would provide a simple, cost-effective method of obtaining enriched neoplastic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.