Article
Targeted RNA sequencing with touch imprint cytology samples for non-small cell lung cancer patients.
Thoracic cancer - 1 Jul 2020
Seto Katsutoshi, Masago Katsuhiro, Fujita Shiro, Haneda Masataka, Horio Yoshitsugu, Hida Toyoaki, Kuroda Hiroaki, Hosoda Waki, Okubo Ken-Ichi
Abstract excerpt
BACKGROUND: RNA-based sequencing is considered ideal for detecting pathogenic fusion-genes compared to DNA-based assays and provides valuable information about the relative expression of driver genes. However, RNA from formalin-fixed paraffin-embedded tissue has issues with both quantity and quality, making RNA-based sequencing difficult in clinical practice. Analyzing stamp-derived RNA with next-generation...
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