Article

Nanopore sequencing from liquid biopsy: analysis of copy number variations from cell-free DNA of lung cancer patients

2020-06-23

Abstract excerpt

<h4>ABSTRACT</h4> Alterations in the genetic content, such as Copy Number Variations (CNVs) is one of the hallmarks of cancer and their detection is used to recognize tumoral DNA. Analysis of cell-free DNA from plasma is a powerful tool for non-invasive disease monitoring in cancer patients. Here we exploit third generation sequencing (Nanopore) to obtain a CNVs profile of tumoral DNA from plasma, where cancer-re...

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Identifiers and source

Literature Corpus work: 74998c9e-f33f-5624-8bd5-cd36437e0e17
DOI: 10.1101/2020.06.22.165555

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