Article
FNA smears as a potential source of DNA for targeted next-generation sequencing of lung adenocarcinomas.
Cancer cytopathology - 1 Jun 2016
Treece Amanda L, Montgomery Nathan D, Patel Nirali M, Civalier Chris J, Dodd Leslie G, Gulley Margaret L, Booker Jessica K, Weck Karen E
Abstract excerpt
BACKGROUND: Diff-Quik-stained fine-needle aspiration (FNA) smears and touch preparations from biopsies represent alternative specimens for molecular testing when cell block or biopsy material is insufficient. This study describes the use of these samples for targeted next-generation sequencing (NGS) of primary and metastatic lung adenocarcinoma and reports the DNA quality and success rates of FNA smears versus...
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