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Nanopore sequencing from liquid biopsy: analysis of copy number variations from cell-free DNA of lung cancer patients

12 Feb 2021

Abstract excerpt

In the "precision oncology" era the characterization of tumor genetic features is a pivotal step in cancer patients' management. Liquid biopsy approaches, such as analysis of cell-free DNA from plasma, represent a powerful and noninvasive strategy to obtain information about the genomic status of the tumor. Sequencing-based analyses of cell-free DNA, currently performed with second generation sequencers, are...

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PMID: 33579306
DOI: 10.1186/s12943-021-01327-5

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