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Article

TRPV1 attenuates intracranial arteriole remodeling through inhibiting VSMC phenotypic modulation in hypertension.

Histochemistry and cell biology - 1 Apr 2017

Zhang Ming-Jie, Liu Yun, Hu Zi-Cheng, Zhou Yi, Pi Yan, Guo Lu, Wang Xu, Chen Xue, Li Jing-Cheng, Zhang Li-Li

Abstract excerpt

The phenotypic modulation of contractile vascular smooth muscle cell (VSMC) is widely accepted as the pivotal process in the arterial remodeling induced by hypertension. This study aimed to investigate the potential role of transient receptor potential vanilloid type 1 (TRPV1) on regulating VSMC plasticity and intracranial arteriole remodeling in hypertension. Spontaneously hypertensive rats (SHR), Wistar-Kyoto...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27774580
DOI: 10.1007/s00418-016-1512-x

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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