Article
Electroacupuncture Attenuated Phenotype Transformation of Vascular Smooth Muscle Cells via PI3K/Akt and MAPK Signaling Pathways in Spontaneous Hypertensive Rats.
Chinese journal of integrative medicine - 1 Apr 2022
Chen Xin-Yu, Yang Lu-Ping, Zheng Ya-Ling, Li Yu-Xi, Zhong Dong-Ling, Jin Rong-Jiang, Li Juan
Abstract excerpt
OBJECTIVE: To investigate whether the antihypertensive mechanism of electroacupuncture (EA) is associated with attenuating phenotype transformation of vascular smooth muscle cells (VSMCs) via phosphoinositide3-kinase (PI3K)/protein kinase B (Akt) and mitogen-activated protein kinase (MAPK) signaling pathways. METHODS: Eight Wistar-ktoyo (WKY) rats were set as normal blood pressure group (normal group). A total of...
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