Article
Vascular smooth muscle cell phenotype is defined by Ca2+-dependent transcription factors.
The FEBS journal - 1 Nov 2013
Kudryavtseva Olga, Aalkjaer Christian, Matchkov Vladimir V
Abstract excerpt
Ca(2+) is an important second messenger in vascular smooth muscle cells (VSMCs). Therefore, VSMCs exercise tight control of the intracellular Ca(2+) concentration ([Ca(2+)]i) by expressing a wide repertoire of Ca(2+) channels and transporters. The presence of several pathways for Ca(2+) influx and efflux provides many possibilities for controlling [Ca(2+)]i in a spatial and temporal manner. Intracellular Ca(2+)...
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