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Article

7-O-methylpunctatin, a Novel Homoisoflavonoid, Inhibits Phenotypic Switch of Human Arteriolar Smooth Muscle Cells.

Biomolecules - 8 Nov 2019

Fardoun Manal, Iratni Rabah, Dehaini Hassan, Eid Assaad, Ghaddar Tarek, El-Elimat Tamam, Alali Feras, Badran Adnan, Eid Ali H, Baydoun Elias

Abstract excerpt

Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from a contractile to a synthetic phenotype. The latter is characterized by increased proliferation, migration, and invasion. Compounds with anti-inflammatory actions have been successful in...

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Identifiers

PMID: 31717401
DOI: 10.3390/biom9110716
PMCID: PMC6920859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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