Article
Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.
Molecular and cellular biology - 1 Nov 2008
Ullah Mukta, Pelletier Nadine, Xiao Lin, Zhao Song Ping, Wang Kainan, Degerny Cindy, Tahmasebi Soroush, Cayrou Christelle, Doyon Yannick, Goh Siew-Lee, Champagne Nathalie, Côté Jacques, Yang Xiang-Jiao
Abstract excerpt
The monocytic leukemia zinc finger protein MOZ and the related factor MORF form tetrameric complexes with ING5 (inhibitor of growth 5), EAF6 (Esa1-associated factor 6 ortholog), and the bromodomain-PHD finger protein BRPF1, -2, or -3. To gain new insights into the structure, function, and regulation of these complexes, we reconstituted them and performed various molecular analyses. We found that BRPF proteins...
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