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Article

PLZF mutation alters mouse hematopoietic stem cell function and cell cycle progression.

Blood - 14 Apr 2016

Vincent-Fabert Christelle, Platet Nadine, Vandevelde Amelle, Poplineau Mathilde, Koubi Myriam, Finetti Pascal, Tiberi Guillaume, Imbert Anne-Marie, Bertucci François, Duprez Estelle

Abstract excerpt

Hematopoietic stem cells (HSCs) give rise to all blood populations due to their long-term self-renewal and multipotent differentiation capacities. Because they have to persist throughout an organism's life span, HSCs tightly regulate the balance between proliferation and quiescence. Here, we investigated the role of the transcription factor promyelocytic leukemia zinc finger (plzf) in HSC fate using the...

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Identifiers

PMID: 26941402
DOI: 10.1182/blood-2015-09-666974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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