Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers.

Oncotarget - 8 Nov 2016

Rizzolo Piera, Navazio Anna Sara, Silvestri Valentina, Valentini Virginia, Zelli Veronica, Zanna Ines, Masala Giovanna, Bianchi Simonetta, Scarnò Marco, Tommasi Stefania, Palli Domenico, Ottini Laura

Abstract excerpt

Male breast cancer (MBC) is a rare disease. Due to its rarity, MBC research and clinical approach are mostly based upon data derived from its largely known female counterpart. We aimed at investigating whether MBC cases harbor somatic alterations of genes known as prognostic biomarkers and molecular therapeutic targets in female breast cancer.We examined 103 MBC cases, all characterized for germ-line BRCA1/2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Breast Neoplasms, Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Class I Phosphatidylinositol 3-Kinases

Share to DNA Copy Number Variations

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Germ-Line Mutation

Share to Oncogenes

Source

Open in PubMed Open full text

Identifiers

PMID: 27765917
DOI: 10.18632/oncotarget.12272
PMCID: PMC5342038

Genes

BRCA1
EGFR
ESR1
CCND1
MIB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers.PMID 27765917Read ↗

The molecular genetic make-up of male breast cancerSemantic proximity Read ↗

Clinicopathological and genetic analysis of 55 male patients with invasive breast cancerSemantic proximity Read ↗

The Genomic Landscape of Male Breast Cancers.Semantic proximity Read ↗

Genomic profiling and comparative analysis of male versus female metastatic breast cancer across subtypes.Semantic proximity Read ↗

DNA damage response as a prognostic indicator in metastatic breast cancer via mutational analysisSemantic proximity Read ↗

Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations.Semantic proximity Read ↗

EMSY copy number variation in male breast cancers characterized for BRCA1 and BRCA2 mutations.Semantic proximity Read ↗

The cancer genetics and pathology of male breast cancer.Semantic proximity Read ↗

Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis.Semantic proximity Read ↗

Male Breast Cancer: From Molecular Genetics to Clinical ManagementSemantic proximity Read ↗

Identification of a new BRCA2 large genomic deletion associated with high risk male breast cancerSemantic proximity Read ↗

Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.