The Genomic Landscape of Male Breast Cancers.

doi:10.1158/1078-0432.CCR-15-2840

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The Genomic Landscape of Male Breast Cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2016

Piscuoglio Salvatore, Ng Charlotte K Y, Murray Melissa P, Guerini-Rocco Elena, Martelotto Luciano G, Geyer Felipe C, Bidard Francois-Clement, Berman Samuel, Fusco Nicola, Sakr Rita A, Eberle Carey A, De Mattos-Arruda Leticia, Macedo Gabriel S, Akram Muzaffar, Baslan Timour, Hicks James B, King Tari A, Brogi Edi, Norton Larry, Weigelt Britta, Hudis Clifford A, Reis-Filho Jorge S

Abstract excerpt

PURPOSE: Male breast cancer is rare, and its genomic landscape has yet to be fully characterized. Lacking studies in men, treatment of males with breast cancer is extrapolated from results in females with breast cancer. We sought to define whether male breast cancers harbor somatic genetic alterations in genes frequently altered in female breast cancers. EXPERIMENTAL DESIGN: All male breast cancers were estrogen...

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PMID: 26960396
DOI: 10.1158/1078-0432.CCR-15-2840
PMCID: PMC4987160

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