Article
Genomic profiling and comparative analysis of male versus female metastatic breast cancer across subtypes.
Breast cancer research : BCR - 24 Jul 2024
Kadamkulam Syriac Arun, Nandu Nitish Singh, Clark Allison, Tavallai Mehrad, Jin Dexter X, Sokol Ethan, McGregor Kimberly, Ross Jeffrey S, Danziger Natalie, Leone Jose Pablo
Abstract excerpt
BACKGROUND: Male breast cancer (MaBC) has limited data on genomic alterations. We aimed to comprehensively describe and compare MaBC's genomics with female breast cancer's (FBC) across subtypes. METHODS: Using genomic data from Foundation Medicine, we categorized 253 MaBC into estrogen receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative (n = 210), ER-positive/HER2-positive (n = 22) and...
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